Time to First Patient · Monthly

What actually happens between protocol and first patient

One issue a month for teams running study startup, covering the work from feasibility through activation. The source population and timeframe stay beside every claim.

Preview from Issue 01
Pre-activation amendments
The amendment that arrives before the study opens

Most activation reporting starts its clock at activation. That sounds obvious until you notice what it excludes: every amendment that lands while the study is still in startup never appears in the number at all.

4 to 6 weeksmost commonly reported delay when an amendment was received, in a fall 2025 survey of 43 AACI member sites

The rework is not one team’s. A change to the schedule of assessments moves the budget, which moves the contract…

What you get

What arrives each month

01

One startup problem at a time

Each issue follows one startup problem far enough to show what causes it and where the time goes.

02

Numbers with their limits

Survey size, population and timeframe stay attached to every claim.

03

Product news stays separate

A short, labeled product note may appear at the end. Subscribing does not start a sales follow-up.

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